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Thursday, February 28, 2013
New cancer 'vaccine' shows future promise in treating and preventing metastatic cancers
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Public release date: 27-Feb-2013[ | E-mail |
Share ] Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University
Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from a recent study show the therapy could treat metastatic cancers and be used in combination with current cancer therapies while helping to prevent the development of new metastatic tumors and train specialized immune system cells to guard against cancer relapse.
Recently published in the journal Cancer Research, the study detailed the effects of a molecule engineered by lead author Xiang-Yang Wang, Ph.D., on animal and cell models of melanoma, prostate and colon tumors. The molecule called Flagrp-170 consists of two distinct proteins, glucose-regulated protein 170 (Grp170), known as a "molecular chaperone," and a "danger signal" derived from flagellin, a protein commonly found in bacteria. The researchers used modified viruses, or adenoviruses, that can no longer replicate to transport Flagrp-170 directly to the tumor site to achieve localized vaccination. The novel therapy caused a profound immune response that significantly prolonged survival in animal models.
"Successfully promoting antitumor immunity will help eradicate tumor cells, control cancer progression and help prevent tumor relapse," says Wang, Harrison Scholar, member of the Cancer Molecular Genetics research program at VCU Massey Cancer Center and associate professor of Human and Molecular Genetics at VCU School of Medicine. "This immunotherapy has the potential to be used alone or in combination with conventional cancer treatments to develop and establish immune protection against cancer and its metastases."
Grp170 is currently being explored for its potential as a "cancer vaccine" because it has been shown to help the immune system recognize cancer antigens. Antigens are molecules from foreign objects such as bacteria, viruses or cancer that, when detected, provoke an immune response aimed at attacking them. However, because cancer cells can alter the microenvironment surrounding a tumor, they are able to suppress immune responses and continue replicating without being attacked by the body's natural defenses.
The chimeric chaperone Flagrp-170, created by strategically fusing a fragment of flagellin to Grp170, not only enhances antigen presentation, it also stimulates additional immune signals essential for functional activation of specialized immune cells, including dendritic cells, CD8+ T lymphocytes and natural killer (NK) cells. Dendritic cells act as messengers between the innate and adaptive immune systems. Once activated in response to a stimulus such as Flagrp-170, dendritic cells migrate to lymph nodes where they interact with other immune cells such as T lymphocytes to shape the body's immune response. CD8+ T lymphocytes and NK cells are known to respond to tumor formation and kill cancer cells by triggering apoptosis, a form of cell suicide.
"Overcoming cancer's ability to suppress the body's natural immune responses and restore or develop immunity for tumor eradication is the goal of cancer immunotherapy," says Wang. "More experiments are needed, but we are hoping Flagrp-170 may one day be used in formulating more effective therapeutic cancer vaccines."
Moving forward, Wang and his team are working to better understand the molecular mechanisms responsible for Flagrp-170's therapeutic effects. Additional studies are underway to more efficiently target and deliver Flagrp-170 to tumor sites in order to provoke a more robust and durable immune response.
###
Wang collaborated on this research with Paul Fisher, M.Ph., Ph.D., Thelma Newmeyer Corman Endowed Chair in Cancer Research and program co-leader of Cancer Molecular Genetics at VCU Massey Cancer Center, chairman of VCU's Department of Human and Molecular Genetics and director of the VCU Institute of Molecular Medicine; Xiaofei Yu; Chunquing Guo, Ph.D.; Huanfa Yi; and Jie Qian, Ph.D., all from VCU's Department of Human and Molecular Genetics and the VCU Institute of Molecular Medicine; and John R. Subjeck from the Department of Cellular Stress Biology at Roswell Park Cancer Institute.
This research was supported by NIH grants CA129111 and CA154708; the American Cancer Society, the Department of Defense and, in part, by funding from VCU Massey Cancer Center's NIH-NCI Cancer Center Support Grant P30 CA016059.
The full manuscript of this study is available online at: http://cancerres.aacrjournals.org/content/early/2013/01/18/0008-5472.CAN-12-1740.long.
News directors: Broadcast access to VCU Massey Cancer Center experts is available through VideoLink ReadyCam. ReadyCam transmits video and audio via fiber optics through a system that is routed to your newsroom. To schedule a live or taped interview, contact John Wallace.
About VCU Massey Cancer Center:
VCU Massey Cancer Center is one of only 67 National Cancer Institute-designated institutions in the country that leads and shapes America's cancer research efforts. Working with all kinds of cancers, the Center conducts basic, translational and clinical cancer research, provides state-of-the-art treatments and clinical trials, and promotes cancer prevention and education. Since 1974, Massey has served as an internationally recognized center of excellence. It has one of the largest offerings of clinical trials in Virginia and serves patients in Richmond and in four satellite locations. Its 1,000 researchers, clinicians and staff members are dedicated to improving the quality of human life by developing and delivering effective means to prevent, control and ultimately to cure cancer. Visit Massey online at www.massey.vcu.edu or call 877-4-MASSEY for more information.
About VCU and the VCU Medical Center:
Virginia Commonwealth University is a major, urban public research university with national and international rankings in sponsored research. Located in downtown Richmond, VCU enrolls more than 31,000 students in 222 degree and certificate programs in the arts, sciences and humanities. Sixty-six of the programs are unique in Virginia, many of them crossing the disciplines of VCU's 13 schools and one college. MCV Hospitals and the health sciences schools of Virginia Commonwealth University compose the VCU Medical Center, one of the nation's leading academic medical centers. For more, see www.vcu.edu.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 27-Feb-2013[ | E-mail |
Share ] Contact: John Wallace
wallacej@vcu.edu
804-628-1550
Virginia Commonwealth University
Preclinical, laboratory studies suggest a novel immunotherapy could potentially work like a vaccine against metastatic cancers, according to scientists at Virginia Commonwealth University Massey Cancer Center. Results from a recent study show the therapy could treat metastatic cancers and be used in combination with current cancer therapies while helping to prevent the development of new metastatic tumors and train specialized immune system cells to guard against cancer relapse.
Recently published in the journal Cancer Research, the study detailed the effects of a molecule engineered by lead author Xiang-Yang Wang, Ph.D., on animal and cell models of melanoma, prostate and colon tumors. The molecule called Flagrp-170 consists of two distinct proteins, glucose-regulated protein 170 (Grp170), known as a "molecular chaperone," and a "danger signal" derived from flagellin, a protein commonly found in bacteria. The researchers used modified viruses, or adenoviruses, that can no longer replicate to transport Flagrp-170 directly to the tumor site to achieve localized vaccination. The novel therapy caused a profound immune response that significantly prolonged survival in animal models.
"Successfully promoting antitumor immunity will help eradicate tumor cells, control cancer progression and help prevent tumor relapse," says Wang, Harrison Scholar, member of the Cancer Molecular Genetics research program at VCU Massey Cancer Center and associate professor of Human and Molecular Genetics at VCU School of Medicine. "This immunotherapy has the potential to be used alone or in combination with conventional cancer treatments to develop and establish immune protection against cancer and its metastases."
Grp170 is currently being explored for its potential as a "cancer vaccine" because it has been shown to help the immune system recognize cancer antigens. Antigens are molecules from foreign objects such as bacteria, viruses or cancer that, when detected, provoke an immune response aimed at attacking them. However, because cancer cells can alter the microenvironment surrounding a tumor, they are able to suppress immune responses and continue replicating without being attacked by the body's natural defenses.
The chimeric chaperone Flagrp-170, created by strategically fusing a fragment of flagellin to Grp170, not only enhances antigen presentation, it also stimulates additional immune signals essential for functional activation of specialized immune cells, including dendritic cells, CD8+ T lymphocytes and natural killer (NK) cells. Dendritic cells act as messengers between the innate and adaptive immune systems. Once activated in response to a stimulus such as Flagrp-170, dendritic cells migrate to lymph nodes where they interact with other immune cells such as T lymphocytes to shape the body's immune response. CD8+ T lymphocytes and NK cells are known to respond to tumor formation and kill cancer cells by triggering apoptosis, a form of cell suicide.
"Overcoming cancer's ability to suppress the body's natural immune responses and restore or develop immunity for tumor eradication is the goal of cancer immunotherapy," says Wang. "More experiments are needed, but we are hoping Flagrp-170 may one day be used in formulating more effective therapeutic cancer vaccines."
Moving forward, Wang and his team are working to better understand the molecular mechanisms responsible for Flagrp-170's therapeutic effects. Additional studies are underway to more efficiently target and deliver Flagrp-170 to tumor sites in order to provoke a more robust and durable immune response.
###
Wang collaborated on this research with Paul Fisher, M.Ph., Ph.D., Thelma Newmeyer Corman Endowed Chair in Cancer Research and program co-leader of Cancer Molecular Genetics at VCU Massey Cancer Center, chairman of VCU's Department of Human and Molecular Genetics and director of the VCU Institute of Molecular Medicine; Xiaofei Yu; Chunquing Guo, Ph.D.; Huanfa Yi; and Jie Qian, Ph.D., all from VCU's Department of Human and Molecular Genetics and the VCU Institute of Molecular Medicine; and John R. Subjeck from the Department of Cellular Stress Biology at Roswell Park Cancer Institute.
This research was supported by NIH grants CA129111 and CA154708; the American Cancer Society, the Department of Defense and, in part, by funding from VCU Massey Cancer Center's NIH-NCI Cancer Center Support Grant P30 CA016059.
The full manuscript of this study is available online at: http://cancerres.aacrjournals.org/content/early/2013/01/18/0008-5472.CAN-12-1740.long.
News directors: Broadcast access to VCU Massey Cancer Center experts is available through VideoLink ReadyCam. ReadyCam transmits video and audio via fiber optics through a system that is routed to your newsroom. To schedule a live or taped interview, contact John Wallace.
About VCU Massey Cancer Center:
VCU Massey Cancer Center is one of only 67 National Cancer Institute-designated institutions in the country that leads and shapes America's cancer research efforts. Working with all kinds of cancers, the Center conducts basic, translational and clinical cancer research, provides state-of-the-art treatments and clinical trials, and promotes cancer prevention and education. Since 1974, Massey has served as an internationally recognized center of excellence. It has one of the largest offerings of clinical trials in Virginia and serves patients in Richmond and in four satellite locations. Its 1,000 researchers, clinicians and staff members are dedicated to improving the quality of human life by developing and delivering effective means to prevent, control and ultimately to cure cancer. Visit Massey online at www.massey.vcu.edu or call 877-4-MASSEY for more information.
About VCU and the VCU Medical Center:
Virginia Commonwealth University is a major, urban public research university with national and international rankings in sponsored research. Located in downtown Richmond, VCU enrolls more than 31,000 students in 222 degree and certificate programs in the arts, sciences and humanities. Sixty-six of the programs are unique in Virginia, many of them crossing the disciplines of VCU's 13 schools and one college. MCV Hospitals and the health sciences schools of Virginia Commonwealth University compose the VCU Medical Center, one of the nation's leading academic medical centers. For more, see www.vcu.edu.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-02/vcu-nc022713.php
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Cuts imminent, Senate Democrats, GOP stage votes
FILE - In this Feb. 26, 2013 file photo, Senate Majority Leader Harry Reid of Nev. speaks on Capitol Hill in Washington. President Barack Obama will meet Friday with the top leaders in the House and Senate to discuss what to do about automatic cuts to the federal budget, White House and congressional leaders said. The meeting is set to take place hours after the $85 billion in across-the-board cuts will have officially kicked in. This suggests both sides are operating under the assumption a deal won't be reached to avert the cuts ahead of the March 1 deadline. (AP Photo/J. Scott Applewhite, File)
FILE - In this Feb. 26, 2013 file photo, Senate Majority Leader Harry Reid of Nev. speaks on Capitol Hill in Washington. President Barack Obama will meet Friday with the top leaders in the House and Senate to discuss what to do about automatic cuts to the federal budget, White House and congressional leaders said. The meeting is set to take place hours after the $85 billion in across-the-board cuts will have officially kicked in. This suggests both sides are operating under the assumption a deal won't be reached to avert the cuts ahead of the March 1 deadline. (AP Photo/J. Scott Applewhite, File)
WASHINGTON (AP) ? Squabbling away the hours, the Senate moved toward certain defeat of last-minute plans to avoid $85 billion in broad-based spending reductions Thursday as the two political parties blamed each other for the latest outbreak of gridlock and the Obama administration readied plans to put the cuts into effect.
The immediate impact was uncertain as the administration pulled back on its earlier warnings of long lines developing quickly at airports and teacher layoffs affecting classrooms. But there was no doubt about the outcome of back-to-back votes on the Senate floor.
There, a Republican plan requiring Obama to propose an alternative package of $85 billion in cuts faced rejection at the hands of Democrats.
And, just as surely, a Democratic proposal to spread the cuts over a decade and replace half of them with higher taxes on millionaires and corporations headed for defeat at Republican hands.
"We have the opportunity to avoid the kind of calamity and disaster that is being threatened and is completely unnecessary," said Sen. Pat Toomey of Pennsylvania, who co-authored the Republican proposal.
"The question is, are we going to achieve these savings through badly designed spending cuts that make no attempt whatever to distinguish between more sensible government spending and less sensible spending?"
Sen. Patty Murray of Washington said that sensible distinguishing was precisely what Democrats had tried to do by proposing the deferral of Pentagon cuts until U.S. combat troops have come home from Afghanistan in two years' time.
At the same time, she said the Democrats had reasonably proposed replacing half of the pending cuts with higher taxes on "the wealthiest Americans and biggest corporations."
Across the Capitol, House Speaker John Boehner led the chorus of Republican critics, saying that "Obama and Senate Democrats are demanding more tax hikes to fuel more 'stimulus' spending."
In fact, the Democratic measure included small increases in funding for a variety of small programs such as biodiesel education, assistance for biomass crops and certification of organic foods.
With no last-minute plans to seek a delay in the looming cuts, Obama invited Boehner and the other top leaders of Congress to a White House meeting on the subject on Friday.
It was not clear whether he would seek negotiations to replace the across-the-board cuts before they begin to bite.
But already, some Republicans held out hope the current struggle might lead to talks on completing work on the final piece of a deficit reduction package that has been more than two agonizing years in the making.
"The objective here ought to be not just to deal with sequester but to deal with the underlying spending problems, which require tax reform" as well as reform of benefit programs like Medicare, Medicaid and Social Security," said Sen. Rob Portman, R-Ohio.
In a cycle of crisis followed by compromise over the past two years, Obama and congressional Republicans have agreed to more than $3.6 trillion in long-term deficit savings over a decade. While much of that has come from spending restraint, the GOP let legislation pass late last year that raises taxes on upper-income Americans by $600 million.
None of the savings to date has come from the big benefit programs that lawmakers in both parties say must be tackled if the country is to gain control over its finances. Each party fears the political fallout of confronting them on their own, but Democrats, in particular, are reluctant to scale back programs that they count as their political birthright.
Their rival speeches on the Senate floor weren't the first time that Toomey and Murray disagreed on economic issues.
Both served on a so-called congressional Supercommittee in 2011 that was charged with producing at least $1.2 trillion in savings over a decade.
The panel deadlocked, automatically triggering the across-the-board cuts that now are imminent.
As constituted, the cuts would total $85 billion through the end of the current budget year ? Sept. 30 ? half each from defense and non-defense programs. Large parts of the budget are off-limits, including programs for veterans, Social Security and Medicare benefits.
The Republican alternative would require Obama to propose an alternative that relied exclusively on spending cuts, ruled out tax increases and limited what he could take from Pentagon accounts. Congress could reject his new approach, but under the alternative, his recommendations would be likely to take effect.
The Democratic measure would have canceled the $85 billion in cuts, and replaced them with a combination of tax increases and cuts to defense and farm programs that would phase in over a decade. Under that plan, deficits would rise by more $42 billion in the first year and $38 billion over the two following years before gradually beginning to decline.
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Wednesday, February 27, 2013
Video: Apple Left Out of the Rally
Sorry, Readability was unable to parse this page for content.
Source: http://video.msnbc.msn.com/cnbc/50979447/
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How budget cuts could affect you
WASHINGTON (AP) ? Government agencies are already taking steps to comply with automatic spending cuts scheduled to take effect Friday.
?Defense Department
One of the Navy's premiere warships, the aircraft carrier USS Harry S. Truman, sits pier-side in Norfolk, Va., its tour of duty delayed.
The carrier and its 5,000-person crew were to leave for the Persian Gulf on Feb. 8, along with the guided-missile cruiser USS Gettysburg.
?Department of Homeland Security
Hundreds of illegal immigrants have been freed from jail across the country.
Immigration and Customs Enforcement officials say they had reviewed several hundred cases of immigrants and decided to put them on an "appropriate, more cost-effective form of supervised release" in a moved started Tuesday.
___
Other steps are planned.
?U.S. Coast Guard
Coast Guard rescue aircraft will fly fewer hours and cutters will patrol the seas for fewer hours, says the service's Commandant Adm. Robert J. Papp.
Emergencies will be a priority and interdictions of illegal immigrants, drugs and illegal fishing could decline.
?Health Care
Hospitals, doctors and other Medicare providers will see a 2 percent cut in government reimbursements because once cutback takes effect, Medicare will reimburse them at 98 cents on the dollar.
But they aren't complaining because the pain could be a lot worse if President Barack Obama and congressional Republicans actually did reach a sweeping agreement to reduce federal deficits. Automatic cuts taking effect Friday would reduce Medicare spending by about $100 billion over a decade. But Obama had put on the table $400 billion in health care cuts, mainly from Medicare. And Republicans wanted more.
?Transportation Department
The nation's busiest airports could be forced to close some of their runways, causing widespread flight delays and cancellations.
Transportation Secretary Ray LaHood predicts flights to cities like New York, Chicago and San Francisco could have delays of up to 90 minutes during peak hours because fewer controllers will be on duty.
Though the spending cuts are scheduled to go into effect on Friday, furloughs of controllers won't kick in until April because the Federal Aviation Administration is required by law to give its employees advance notice. In addition to furloughs, the FAA is planning to eliminate midnight shifts for air traffic controllers at 60 airport towers, close over 100 control towers at smaller airports and reduce preventative maintenance of equipment.
?Federal workers
More than half of the nation's 2.1 million government workers may be required to take furloughs if agencies are forced to trim budgets.
At the Pentagon alone that could mean 800,000 civilian workers would be off for 22 days each, spread across more than five months ? and lose 20 percent of their pay over that period.
Other federal agencies are likely to furlough several hundred thousand more workers.
?Education
Some 70,000 students currently enrolled in pre-kindergarten Head Start would be cut from the program and 14,000 teachers would lose their jobs. For students with special needs, the cuts would eliminate some 7,200 teachers and aides. Up to 29 million student loan borrowers and some lenders may have to lay off staff or even close; some of the 15 million college students who receive grants or work-study assignments at some 6,000 colleges would also see changes.
?National parks
Visiting hours at all 398 national parks are likely to be cut and sensitive areas would be blocked off to the public. Thousands of seasonal workers looking for jobs would not be hired, according to Interior Secretary Ken Salazar.
Salazar and National Park Service director Jon Jarvis said visitors would encounter fewer rangers, locked restrooms and trashcans emptied less frequently.
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Local warming: U.S. cities in front line as sea levels rise
NORFOLK, Virginia (Reuters) - The signs of rising water are everywhere in this seaport city: yellow "Streets May Flood" notices are common at highway underpasses, in low-lying neighborhoods and along the sprawling waterfront.
Built at sea level on reclaimed wetland, Norfolk has faced floods throughout its 400-year history. But as the Atlantic Ocean warms and expands, and parts of the city subside, higher tides and fiercer storms seem to hit harder than they used to.
Dealing with this increased threat has put Norfolk at the forefront of American cities taking the lead on coping with intense weather, from floods to droughts to killer heat, without waiting for the federal government to take the lead.
In Norfolk, home to the largest U.S. Naval base and the second biggest commercial port on the U.S. Atlantic coast, floods are a perennial problem that has worsened in recent decades, Assistant City Manager Ron Williams Jr told Reuters.
The relative sea level around Norfolk has risen 14.5 inches (.37 meter) since 1930, when the low-lying downtown area routinely flooded. The floods are worse now, because the water doesn't have to rise as high to send the river above its banks and into the streets, Williams said.
At the same time, severe storms are more frequent.
"We've had more major storms in the past decade than we've had in the previous four decades," he said.
Extreme rainfall events have increased too.
Williams does not call what's happening in Norfolk a symptom of climate change.
"The debate about causality we're not going to get into," he said.
Still, many scientists see the frequent flooding as consistent with projected consequences of rising global temperatures, spurred by increased emissions of greenhouse gases.
INFRASTRUCTURE PROJECTS PAY OFF
No matter what city leaders call it, some of their actions speak louder than words.
Williams said Norfolk, a city of 243,000, needs a total investment of $1 billion in the coming decades, including $600 million to replace current infrastructure, to keep the water in its place and help make homes and businesses more resilient.
Paying for it will be a burden, Williams said. The city is working with the state legislature and the U.S. Army Corps of Engineers, and hoping federal block grants will help too.
One proposed project, a flood wall to protect the historic Ghent neighborhood and others, would cost an estimated $20 million to $40 million.
Williams said a similar barrier completed in 1970 banished perennial floods from what is now the high-rise downtown. That provided a great return on a $5 million investment, Williams said, with $500 million in assessed real estate value in the area that used to flood but now doesn't.
These measures have made Norfolk a leader for other coastal cities on how to adapt to climate change, said Cynthia Rosensweig, a NASA climate scientist who advises New York City on its response. Rosensweig, Williams and others note that building resilience into infrastructure before disasters hit is far less expensive than rebuilding afterwards.
Henry Conde, a retired U.S. Navy captain who lives in Ghent, said he and his neighbors feel the flood threat viscerally: "There's a low-grade fever, so to speak, or an awareness throughout the year. People are always on edge."
Armpit-high waders, stand-alone generators and sump pumps are standard equipment for when the floods come and the power goes out, Conde said in an interview at his 115-year-old home. Winter nor'easters can be just as bad as summer hurricanes and preparing for the worst beforehand instead of mopping up later is simply an economic reality, he said.
Superstorm Sandy's strike on New Jersey and New York in late October heightened awareness of the need to prepare for incoming water. Sea levels are rising along almost every part of the U.S. coastline, except in Alaska, according to the National Oceanic and Atmospheric Administration ( http://tidesandcurrents.noaa.gov/sltrends/sltrends.shtml ).
Nearly three-quarters of U.S. cities see environmental shifts that can be linked to climate change, but they lag behind the rest of the world when it comes to planning how to adapt to these changes and assessing how vulnerable they are, according to a survey by the Massachusetts Institute of Technology and the non-profit International Council on Local Environmental Initiatives, or ICLEI.
U.S. cities have traditionally focused more on mitigating climate change than adapting to it, the opposite of most cities in the developing world, where vulnerability to climate-fueled natural disasters is already high, said ICLEI's U.S. program director Brian Holland.
More than 1,000 city leaders have signed the U.S. Conference of Mayors Climate Protection Agreement (http://www.usmayors.org/climateprotection/agreement.htm), in which they promise to try to beat global targets to cut greenhouse gas emissions in their communities and urge Congress to pass carbon-cutting laws.
But labeling it global warming can be dicey, given that there is still controversy, particularly among politicians, over whether human activity is contributing markedly to increasing temperatures.
"Given the politicized view of climate change in this country, it seems that some cities are emphasizing risk management - that way they can get on with the important tasks of reducing risk and safeguarding local residents and municipal assets," said MIT's JoAnn Carmin, author of the 2012 survey of 468 cities worldwide, including 298 in the United States.
Still, city leaders can often reach consensus and act more easily than some members of Congress can, said Jim Brainard, the Republican mayor of Carmel, Indiana, and head of the Energy Independence Task Force for the U.S. Conference of Mayors. One reason for this is that lobbyists opposed to climate measures rarely target mayors or other community leaders, he added.
(Reporting By Deborah Zabarenko.; Editing by Ros Krasny and Andre Grenon)
Source: http://news.yahoo.com/local-warming-u-cities-front-line-sea-levels-122926860--finance.html
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Gold Fields Go From Australia To MTV's Artists To Watch
The Australian band will release their full-length debut, Black Sun on Tuesday.
By James Montgomery, with reporting by Cory Midgarden
Gold Fields
Photo: MTV News
Source: http://www.mtv.com/news/articles/1702592/gold-fields-mtv-artist-to-watch.jhtml
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Tuesday, February 26, 2013
Review: Keith McMillen QuNeo Pad Controller
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Monday, February 25, 2013
MasterCard MasterPass Augments Your Digital Shopping Experience
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We're live from ZTE's MWC 2013 press event!
ZTE is chasing the premium smartphone experience -- and it might not come with too heavy a price tag. While we've already seen its skinny phone-tablet, expect some news on a more global appearance, alongside, hopefully, more news on its Nubia range. Oh, and finally a closer look at that Firefox phone -- unless Mozilla has that on lock-down. The event will kick off Sunday at... the time you see below.
February 25, 2013 10:00 AM EST
Filed under: Cellphones, Mobile
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/7SNOV_i7zQA/
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2 scuba divers die off California's Monterey County coast
By 2 hours 32 minutes ago
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Two scuba divers have died while diving off the coast of California's Monterey County, authorities said.
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Emergency crews were sent to Point Lobos State Natural Reserve around 2:45 p.m. Friday where they found lifeguards performing CPR on one of the divers, said state Department of Forestry and Fire Protection spokesman Daniel Berlant.
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Lifeguards and firefighters used a boat to get to second diver floating just offshore.
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"At that point, we got in a boat with State Parks lifeguards and located the second victim floating in the water about 50 feet from the rocks," Capt. Carlos Aguilera of the Carmel Highlands Fire Department told The Monterey County Herald.
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CPR was also performed on that person, but both divers were pronounced dead after being taken to a hospital, officials said.
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The names, additional details about the victims and what killed them have not been released, but authorities said one was a male and one was a female.
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The reserve where the divers died is a popular diving area about four miles south of Carmel, or about 90 miles south of San Francisco.
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The offshore area forms one of the richest underwater habitats in the world, with wildlife that includes seals, sea lions, sea otters and migrating gray whales, according to the state Parks and Recreation Department website, the agency that operates the reserve.
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Proof of certification is required, and diving is permitted only at two coves within the park, including Whalers Cove, the area where the two stricken divers were found, the website said.
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Parks officials did not immediately return calls to The Associated Press seeking details of the incident.
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Sunday, February 24, 2013
TIMELINE: Ford's 100 years in Louisville
Below is a timeline of Ford?s more than 100 years of vehicle production at Ford?s Louisville Assembly Plant, courtesy Ford Motor Company
Louisville Assembly Plant Timeline
1913:? Louisville Ford Sales and Service Branch at 931 South Third Street begins assembly of 12 Model T's per day.
1914:? Construction begun on a new plant at Third and Eastern Parkway.
Jan.? 2, 1916:? Production of Model T begins at new plant.? An average of 53 employees produce 7000 vehicles per year.
June 1918-March 1919:? Plant occupied by the U.S. Army Mechanical and Medical Corps.
April 1923:? An addition increases assembly capacity from 85 to 200 vehicles per day.
Feb. 2, 1925:? A new assembly plant is opened at 1400 Western Parkway.? It has a capacity of 400 cars per day.
1937:? A major flood of the Mississippi River closes the plant for two months when it is submerged under nine feet of water.
Feb. 15, 1942:? Production of GPW 4x4 army trucks begins.? Civilian car production is ceased on February 24 and civilian truck production on March 31.
Sept.? 1945:? Full-scale civilian production resumes.
1953:? Construction begins of the Louisville Assembly Plant on Fern Valley Road at Grade Lane.? The new plant is part of Ford Motor Company's $1.7 billion postwar expansion program.
April 13, 1955:? The last car is assembled at the old plant.? Transfer of more than 150 truckloads of tools, production equipment and office furniture begins.
April 18, 1955:? The first car produced at the Louisville Assembly Plant is received by Kentucky Governor Lawrence Weatherby.? The plant occupies more than 2 million square feet on a 180-acre site.? It has a capacity of 880 cars and trucks per day, on two shifts.
Oct. 18, 1955:? Louisville Assembly Plant is dedicated.? Ford Division general manager Robert S. McNamara delivers the dedication address.
June 1957:? Edsel production added.
Jan.? 1958:? Heavy truck production added.
Nov.? 15, 1961:? An expansion program to add 90,000 square feet to the Louisville Assembly Plant is announced.
July 30, 1963:? A dinner is held to celebrate both the 50th anniversary of Ford assembly in Louisville and the centennial of Henry Ford's birth.
Sept. 22, 1969:? The last heavy truck built at Louisville Assembly Plant is an ND-1000 diesel tractor.? Medium and heavy truck production is shifted to the newly-opened Kentucky Truck Plant .
April 16, 1973:? Light truck assembly added to car production at Louisville Assembly Plant.
June 12, 1981:? Car assembly ceases, leaving only light truck assembly.? The last car, a gold LTD, is the 3,433,660th passenger car assembled in Louisville since 1913.
September 1981:? Start of a formal Employee Involvement program.
Jan.? 18, 1982:? Ranger production begins.
January 1983:? Bronco II production begins.? A total of 820,931 Bronco II's are produced before the end of production in February 1990.
April 15-19, 1983:? Louisville Assembly Plant celebrates the 70th anniversary of Ford assembly in Louisville with an open house attended by over 55,000 visitors.
Aug. 22, 1984:? Louisville Assembly Plant is presented with a U.S. Senate Productivity Award.
May 1985:? Ford announces a new $78-million automated paint operation at Louisville Assembly Plant.
July 1985:? The 1-millionth Ranger is produced.
July 14, 1987:? Ford Motor Company announces a $260 million expansion to prepare for production of a new vehicle.? The vehicle is later revealed as the Explorer.
April 26, 1988:? The 2-millionth Ranger/Bronco II vehicle is produced at Louisville Assembly Plant.
June 13-17, 1988:? Louisville Assembly Plant celebrates the 75th anniversary of Ford in Louisville.
Feb.? 14, 1990:? The first Ford Explorer is produced at Louisville Assembly Plant.
May 1991:? Louisville Assembly Plant is awarded Ford Motor Company's prestigious Q1 award.
Aug.? 22, 1991:? A new UAW-Ford Education Center is dedicated at Louisville Assembly Plant.
1992:? Production begins of the redesigned Ranger.
November 1992:? A homologation center to modify vehicles for foreign export opens at Louisville Assembly Plant.
May 1993:? Q1 award is recertified.
Aug.? 27, 1993:? Louisville Assembly Plant produces the 1-millionth Ford Explorer.
Nov. 29, 1994:? The redesigned Ford Explorer is launched.
April 1996:? Mercury Mountaineer assembly added.
May 30, 1996:? 2-millionth Explorer produced.
1999:? The Harbour Report names Louisville Assembly Plant most efficient truck plant.
Feb. 3, 2000:? Louisville Assembly Plant hosts the launch of the Explorer Sport Trac.
Sept. 16, 2002:? The 5-millionth Explorer rolls off the line.
May 14, 2003:? Louisville is one of 100 cities on the Ford Centennial Tour.? The two-day celebration at the Louisville Zoo includes classic and modern vehicle displays.
Dec. 9, 2010:? Ford announces a plan to invest $600 million to modernize and re-tool the Louisville Assembly Plant for production of the new Escape
April 2012: Ford assembly teams prepare for all-new 2013 Escape production, training in simulated factory at Louisville plant.
June 13, 2012:? Ford Motor Company, its employees, dealers and suppliers celebrate production of the all-new Ford Escape at the company?s transformed Louisville Assembly Plant, one of several U.S. manufacturing sites where Ford adds jobs to meet strong customer demand for fuel-efficient vehicles.
Source: http://www.whas11.com/news/local/TIMELINE-Fords-100-years-in-Louisville-192514531.html
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Diane Lampert Dead: Songwriter Dies At Age 88
Rick Huxley
Bass player Rick Huxley, one of the founding members of the Dave Clark Five, died on Feb. 11, 2013, at the age of 72. Though the band broke up in 1970, they were inducted into the Rock and Roll Hall of Fame in 2008.
John Kerr
John Kerr, the stage and film actor whose credits include the movie "South Pacific," the thriller "The Pit and the Pendulum" and a Tony Award-winning turn in "Tea and Sympathy," died on Feb. 9, 2013, at the age of 81. He passed away due to heart failure at Huntington Hospital in Pasadena, Calif.
Donald Byrd
Jazz musician Donald Byrd, a leading hard-bop trumpeter of the 1950s who collaborated on dozens of albums with top artists of his time and later enjoyed commercial success with hit jazz-funk fusion records such as "Black Byrd," died on Feb. 4, 2013. He was 80. No details have been released regarding his death.
Mark Balelo
Mark Balelo, an auction house owner featured on the A&E reality TV show "Storage Wars," was found dead on Feb. 11, 2013. He was 40. His death has been declared a <a href="http://www.huffingtonpost.com/2013/02/13/mark-balelo-suicide_n_2674485.html">suicide</a>.
Mary O'Connor
O'Connor, Hugh Hefner's longtime secretary who appeared on the reality series "Girls Next Door," died on Jan. 27, 2013.
Robin Sachs
The British actor died on Feb. 1, 2013, just four days shy of his 62nd birthday. He is best known for playing villainous character Ethan Rayne on the hit series "Buffy The Vampire Slayer," but boasts a full resume and will also be remembered for his roles on "Babylon 5" and "Star Trek: Voyager."
Robert F. Chew
The actor, best known for his role as drug kingpin Proposition Joe on the critically acclaimed HBO series ?The Wire,? died January 17th, 2013, of apparent heart failure in his sleep at his home in Northeast Baltimore. He was 52.
Freddy E
Seattle rapper Freddy E (real name Freddy E. Buhl) died on January 5, 2013, of an apparent self-inflicted gunshot wound. The 22-year-old is believed to have live tweeted the moments leading up to his apparent suicide.
Ned Wertimer
Ned Wertimer (here seen on the left), who appeared on 11 seasons of "The Jeffersons" as Ralph The Doorman, died January 2, 2013, at the age of 89. Wertimer died following health complications at the Sherman Village Health Care Center in California.
Pauline Phillips
Pauline Phillips, who as Dear Abby dispensed snappy, sometimes saucy advice to millions of newspaper readers around the world, died Jan. 16, 2013, in Minneapolis after a long battle with Alzheimer's. She was 94.
David R. Ellis
Ellis, the director of "Snakes on a Plane," died in South Africa on January 7, 2013. He was 60.
Jenni Rivera
In this March 8, 2012 file photo, Mexican-American singer and reality TV star Jenni Rivera poses during an interview in Los Angeles. Las Vegas-based Starwood Management, the company that owns the luxury jet that crashed and killed Rivera on Dec. 9, is under investigation by the U.S. Drug Enforcement Administration, and the agency seized two of its planes earlier this year as part of the ongoing probe. (AP Photo/Reed Saxon, File)
Charles Durning
The revered actor, who played everyone from a Nazi colonel to the pope to Dustin Hoffman's would-be suitor in "Tootsie," died of natural causes in New York on December 24, 2012, at the age of 89.
Nora Ephron
Director, author, journalist, playwright, <a href="http://www.huffingtonpost.com/nora-ephron/" target="_hplink">HuffPost blogger</a>, and three-time Academy Award nominated screenwriter, <a href="http://www.huffingtonpost.com/2012/06/26/nora-ephron-dead-dies-age-71_n_1627757.html" target="_hplink">Nora Ephron passed away</a> on June 26 after a <a href="http://www.huffingtonpost.com/2012/06/26/nora-ephron-leukemia-cancer-illness-death_n_1629152.html" target="_hplink">secret multi-year battle with acute myeloid leukemia</a>. With genre defining films like "Sleepless In Seattle", "You've Got Mail", and "When Harry Met Sally", Ephron, 71, <a href="http://www.huffingtonpost.com/2012/06/26/nora-ephron-influence-movies_n_1628700.html?utm_hp_ref=entertainment" target="_hplink">left an indelible mark on the film industry.</a>
Herbert Lom
Herbert Lom, best known as Inspector Clouseau's long-suffering boss in the "Pink Panther" movies, died peacefully in his sleep at home in London on Sept. 27, 2012. He was 95.
Michael Clarke Duncan
"The Green Mile" actor Michael Clarke Duncan died at the age of 54 on Sept. 3, 2012 in a Los Angeles hospital after nearly two months of treatment following a July 13, 2012 heart attack.
Jerry Nelson
"Sesame Street" puppeteer Jerry Nelson, shown here with "Sesame Street" character Count von Count in New York in June 2012, died at age 78 on Aug. 23, 2012, in Massachusetts after battling emphysema.
Conrad Bain
The actor best known for his long run as father Philip Drummond on the hit series "Diff'rent Strokes," died on January 14, 2013, of natural causes in his hometown of Livermore, California. He was 89.
Phyllis Diller
Actress/comedienne Phyllis Diller, who was best know for her stand-up act, <a href="http://www.huffingtonpost.com/2012/08/20/phyllis-diller-dead_n_1812818.html">died at the age of 95</a> on Aug. 20. 2012 in Los Angeles.
Tony Scott
Director Tony Scott, whose projects include "The Hunger," "Top Gun," "Enemy of the State," died after jumping off a bridge in Los Angeles on Aug. 19, 2012.
Scott McKenzie
"San Francisco (Be Sure to Wear Flowers in Your Hair)" singer Scott McKenzie, seen here in the center with "The Mamas And The Papas" 1967, <a href="http://www.huffingtonpost.com/2012/08/20/scott-mckenzie-dead-dies-san-francisco-73_n_1809989.html">died on Aug. 18. 2012</a>, after battling Guillain-Barre Syndrome, a disease that affects the nervous system.
William Windom
A 1980 file photo provided by CBS shows actor William Windom, who won an Emmy Award for his turn in the TV comedy series "My World And Welcome To It," died Aug. 16, 2012, of congestive heart failure at his home in Woodacre, north of San Francisco. He was 88.
Jack Klugman
The "Odd Couple" star died at peacefully in his California home at the age of 90, on Christmas Eve, 2012. In the 1980s, Klugman lost his voice to throat cancer and trained himself to speak again.
Ron Palillo
This June 8, 2008 file photo shows actor Ron Palillo at the TV Land Awards in Santa Monica, Calif. Palillo, best known as the nerdy high schooler Arnold Horshack on "Welcome Back, Kotter," <a href="http://www.huffingtonpost.com/2012/08/14/ron-palillo-dead-dies-welcome-back-kotter-heart-attack_n_1776155.html">died Tuesday, Aug. 14, 2012</a>, in Palm Beach Gardens, Fla., of an apparent heart attack. He was 63.
Lupe Ontiveros
This Oct. 7, 2008 file photo shows actress Lupe Ontiveros at Padres Contra El Cancer's 8th annual "El Sueno de Esperanza" benefit gala in Los Angeles. Ontiveros, the popular Texan actress known for her portrayal of Yolanda Saldivar in "Selena," <a href="http://www.huffingtonpost.com/2012/07/27/lupe-ontiveros-dead-star-_n_1709783.html">died Thursday, July 26, 2012</a>, of cancer at the Presbyterian Hospital in the City of Whittier, Calif., according to friend and comedian Rick Najera. She was 69.
Sherman Hemsley
In this Aug. 11, 1986 file photo, actor Sherman Hemsley poses for a photo in Los Angeles. The manager for Hemsley says the late star of the television sitcom ?"The Jeffersons"? refused treatment for lung cancer in the weeks before he died of what a coroner says were complications from the disease on July 24, 2012. (AP photo/Nick Ut, File)
Frank Pierson
In this Feb. 14, 2004 file photo, Academy President Frank Pierson arrives at the Academy of Motion Picture Arts and Sciences, Scientific and Technical Achievements Awards dinner in Pasadena Calif. Pierson's family announced that <a href="http://www.huffingtonpost.com/2012/07/23/frank-pierson-dead-dog-day-afternoon-dies_n_1696126.html">he died of natural causes on Monday, July 23, 2012</a> in Los Angeles after a short illness. He was 87.
Jon Lord
Deep Purple's Jon Lord, seen here in 2004, died at age 71 on Monday, July 16, 2012, after battling pancreatic cancer.
Whitney Houston
With perhaps one of the <a href="http://www.huffingtonpost.com/2012/05/21/whitney-houston-celebrate-jordin-sparks-sparkle_n_1532870.html" target="_hplink">greatest voices</a> of her generation, Houston was a multi-Grammy winning singer and actress left an indelible mark on both the pop and R&B genres. <a href="http://www.huffingtonpost.com/2012/02/15/whitney-houston-xanax_n_1279947.html" target="_hplink">Houston's well documented struggles with drug addiction</a> are thought to have contributed to her unexpected and <a href="http://www.huffingtonpost.com/2012/02/11/whitney-houston-dead-sing_n_1270889.html" target="_hplink">untimely demise</a> at age 48 on <a href="http://www.huffingtonpost.com/2012/04/05/whitney-houston-death-report-last-day_n_1405206.html" target="_hplink">February 11</a>.
Kitty Wells
This May 1986 file photo shows country music singer Kitty Wells in Nashville, Tenn. Wells, the first female superstar of country music, <a href="http://www.huffingtonpost.com/2012/07/16/kitty-wells-dead-queen-of-country-dies_n_1677532.html">died at the age of 92 on Monday, July 16, 2012.</a> The singer?s family says Wells died at her home Monday after complications from a stroke. Her recording of "It Wasn't God Who Made Honky Tonk Angels" in 1952 was the first No. 1 hit by a woman soloist on the country music charts. Other hits included "Making Believe" and a version of "I Can't Stop Loving You." (AP Photo/Mark Humphrey, file)
Donna Summer
<a href="http://www.huffingtonpost.com/2012/05/18/donna-summer-queen-of-disco_n_1526799.html" target="_hplink">The Queen of Disco</a> lost her <a href="http://www.huffingtonpost.com/2012/05/17/donna-summer-dead-queen-of-disco-dies_n_1524410.html" target="_hplink"> battle with cancer</a> on May 17. Summer, 63, earned that title with dance hits like "Last Dance", "MacArthur Park", and "Hot Stuff".
Ernest Borgnine
Perhaps best remembered for his<a href="http://www.huffingtonpost.com/2012/07/08/ernest-borgnine-movies-films_n_1657787.html" target="_hplink"> Oscar-winning performance in the film "Marty",</a> <a href="http://www.huffingtonpost.com/2012/07/09/ernest-borgnine-dead-remembered_n_1658937.html" target="_hplink">Borgnine</a> continued to act until his death, voicing a character on "SpongeBob SquarePants" and earning an Emmy Nomination on the TV series "ER." He was 95 when he passed away on July 8 due to renal failure.
Andy Griffith
<a href="http://www.huffingtonpost.com/2012/07/03/andy-griffith-dead_n_1645969.html" target="_hplink">Andy Griffith,</a> the star of beloved television programs "The Andy Griffith Show" and "Matlock", <a href="http://www.huffingtonpost.com/2012/07/05/andy-griffith-cause-of-death-heart-attack_n_1652599.html" target="_hplink">died of a heart attack</a> on Tuesday, July 3. He was 86.
Helen Gurley Brown
In this Sept. 20, 1982 file photo, Cosmopolitan editor Helen Gurley Brown poses during an interview at her office in New York. Brown, longtime editor of Cosmopolitan magazine, died on Aug. 13, 2012 at a hospital in New York after a brief hospitalization. She was 90. (AP Photo/Marty Lederhandler, File)
Don Grady
<a href="http://www.huffingtonpost.com/2012/06/28/don-grady-my-three-sons-obituary_n_1633047.html" target="_hplink">The multi talented musician, composer, and actor</a> who memorably starred on the television series "My Three Sons" lost his battle with cancer on June 27. An original Mouseketeer, Grady was 68 he passed away.
Yvette Wilson
Comedienne most famous for her hilarious roles on TV shows "Moesha" and "The Parkers", Wilson <a href="http://www.huffingtonpost.com/2012/06/15/yvette-wilson-star-of-moe_n_1600037.html" target="_hplink">lost her battle with cervical cancer</a> on June 14. She was 48.
Ann Rutherford
This Nov. 5, 1971 file photo shows actress Ann Rutherford in New York. Rutherford, who played Scarlett O'Hara's sister Carreen in the 1939 movie classic "Gone With the Wind," <a href="http://www.huffingtonpost.com/2012/06/12/ann-rutherford-dead-gone-_n_1589753.html">died at her home in Beverly Hills, Calif. on Monday, June 11, 2012</a>. She was 94. (AP Photo/HF)
Robin Gibb
<a href="http://www.huffingtonpost.com/2012/05/23/barry-gibb-tribute-video-robin-gibb-bee-gees_n_1539954.html" target="_hplink">Co-founder of The Bee Gees</a>, Gibb was 62 when he <a href="http://www.huffingtonpost.com/2012/05/20/robin-gibb-dead-bee-gees_n_1531648.html" target="_hplink">lost</a> his battle with colon cancer on May 20.
Bob Welch
From AP: Bob Welch, a former member of Fleetwood Mac who went on to write songs and record several hits during a solo career,<a href="http://www.huffingtonpost.com/2012/06/07/bob-welch-dead-fleetwood-mac-gunshot_n_1579166.html"> died June 7, 2012</a>, of a self-inflicted gunshot wound, police said. He was 65.
Chuck Brown
In this Feb. 13, 2011 file photo, Chuck Brown arrives at the 53rd annual Grammy Awards in Los Angeles. Brown, who styled a unique brand of funk music as a singer, guitarist and songwriter known as the "godfather of go-go," <a href="http://www.huffingtonpost.com/2012/05/16/chuck-brown-dead-godfather_n_1522375.html">died Wednesday, May 16, 2012</a> after suffering from pneumonia. He was 75.
Mitchell Guist
Mitchell Guist, who appeared in segments of the "Swamp People" with his brother, Glenn, <a href="http://www.huffingtonpost.com/2012/05/14/mitchell-guist-dead-swamp-people_n_1515423.html">died after collapsing Monday, May 14, 2012</a> while working on a houseboat he was building on Belle River.
Adam Yauch
Best known as one of the founding members of the<a href="http://www.huffingtonpost.com/2012/05/23/mca-ad-rock-adam-horovitz-beastie-boys-interview_n_1539705.html" target="_hplink"> trailblazing hip-hop group the Beastie Boys</a>, Yauch, also known by his stage name MCA, was also a <a href="http://www.huffingtonpost.com/2012/05/04/adam-yauch-films_n_1478993.html" target="_hplink">film director</a> and <a href="http://www.huffingtonpost.com/2012/05/04/adam-yauch-dead-tibet_n_1478359.html" target="_hplink">human rights activist</a>. At age 47, Yauch unfortunately lost his almost three year battle with cancer on May 4.
George Lindsey
George Lindsey, seen here in character as Goober Pyle on "The Andy Griffith Show" in 1982,<a href="http://www.huffingtonpost.com/2012/05/06/george-lindsey-dead-andy-griffith-show-goober-pyle-dies-83_n_1490083.html"> died early Sunday, May 6, 2012.</a> He was 83.
Levon Helm
In this May 15, 2010 photo, Levon Helm performs on the mandolin during a Ramble performance at Helm's barn in Woodstock, N.Y. Helm, who was in the final stages of his battle with cancer,<a href="http://www.huffingtonpost.com/2012/04/19/levon-helm-dead-the-band-cancer-battle_n_1434772.html"> died Thursday, April 19, 2012 in New York.</a> He was 71. He was a key member of The Band and lent his distinctive Southern voice to classics like "The Weight" and "The Night They Drove Old Dixie Down."
Dick Clark
Radio personality, <a href="http://www.huffingtonpost.com/2012/04/18/dick-clark-quotes_n_1435713.html" target="_hplink">TV host</a>, and <a href="http://www.huffingtonpost.com/nelson-davis/dick-clarks-business-less_b_1466150.html" target="_hplink">beloved producer</a>, Dick Clark died of a <a href="http://www.huffingtonpost.com/2012/04/18/dick-clark-heart-attack-death_n_1435551.html" target="_hplink">massive heart</a> attack on April 18. The host of classic programs such as <a href="http://www.huffingtonpost.com/huff-wires/20120418/us-dick-clark-highlights/" target="_hplink">American Bandstand</a> and <a href="http://www.huffingtonpost.com/2012/04/19/dick-clarks-new-years-eve_n_1437040.html" target="_hplink">Dick Clark's Rocking New Years Eve was 82.</a>
Davy Jones
Lead singer of hit 60's band <a href="http://www.huffingtonpost.com/2012/02/29/davy-jones-dead-monkees-moments-video_n_1310837.html" target="_hplink">The Monkees</a>, Jones' <a href="http://www.huffingtonpost.com/2012/03/01/monkees-davy-jones-obituary_n_1312799.html" target="_hplink">heartthrob status</a> was cemented with hits like "Day Dream Believer" and "I Wanna Be Free". He died at age 66 on February 29 after <a href="http://www.huffingtonpost.com/2012/04/05/davy-jones-autopsy-report_n_1406273.html" target="_hplink">suffering a heart attack</a>.
Don Cornelius
<a href="http://www.huffingtonpost.com/2012/02/01/don-cornelius-dead-soul-train_n_1246642.html" target="_hplink">Cornelius</a>, creator and host of the long-running, groundbreaking<a href="http://www.huffingtonpost.com/2012/02/01/don-cornelius-dead-celeb-tweets_n_1247021.html" target="_hplink"> TV dance show "Soul Train,"</a> <a href="http://www.huffingtonpost.com/2012/04/24/don-cornelius-autopsy-depression_n_1450184.html" target="_hplink">committed suicide </a> on Feb. 1. He was 75.
Ian Abercrombie
In this Sept. 17, 2005 file photo, actor Ian Abercrombie is shown during the British Academy of Film and Television Arts/Los Angeles and the Academy of Television Arts & Sciences third annual Emmy Nominees Tea Party in Los Angeles. Abercrombie, a veteran British stage and screen actor whose TV roles included Elaine?s boss Mr. Pitt on "Seinfeld" and Professor Crumbs on ?Wizards of Waverly Place,?<a href="http://www.huffingtonpost.com/2012/01/28/ian-abercrombie-tv-moments_n_1239120.html"> died Thursday, Jan. 22, 2012</a> at a Los Angeles hospital from complications of kidney failure. He was 77.
Etta James
The "At Last" crooner <a href="http://http://www.huffingtonpost.com/2012/01/20/etta-james-dead-legendary_n_1219083.html" target="_hplink">passed away</a> on January 20 due to complications from leukemia. James, also known as <a href="http://www.huffingtonpost.com/2012/01/22/etta-james-singers-passio_n_1222010.html" target="_hplink">The Matriarch of R&B</a>, was 73.
Andy Williams
This Feb. 23, 1978 file photo shows performer and host Andy Williams at the Grammy Awards in Los Angeles. Williams, who had a string of gold albums and hosted several variety shows and specials like "The Andy Williams Show," died Tuesday, Sept. 25, 2012, at his home in Branson, Missouri, following a yearlong battle with bladder cancer, his Los Angeles-based publicist, Paul Shefrin, said Wednesday. He was 84. (AP Photo/Lennox McLendon, file)
Ravi Shankar
In this Feb. 7, 2012 file photo, Indian musician Ravi Shankar performs during a concert in Bangalore, India. Shankar, the sitar virtuoso who became a hippie musical icon of the 1960s after hobnobbing with the Beatles and who introduced traditional Indian ragas to Western audiences over an eight-decade career, has died. He was 92. (AP Photo/Aijaz Rahi, File)
Source: http://www.huffingtonpost.com/2013/02/24/diane-lampert-dead-dies_n_2753140.html
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NKorea warns US commander in SKorea over drills
A South Korean army soldier patrols inside the barbed-wire fence at Imjingak in Paju near the demilitarized zone (DMZ) of Panmunjom, South Korea, Sunday, Feb. 17, 2013. North Korea is upgrading one of its two major missile launch sites, apparently to handle much bigger rockets, and some design features suggest it is getting help from Iran, a U.S. research institute said last Thursday. (AP Photo/Ahn Young-joon)
A South Korean army soldier patrols inside the barbed-wire fence at Imjingak in Paju near the demilitarized zone (DMZ) of Panmunjom, South Korea, Sunday, Feb. 17, 2013. North Korea is upgrading one of its two major missile launch sites, apparently to handle much bigger rockets, and some design features suggest it is getting help from Iran, a U.S. research institute said last Thursday. (AP Photo/Ahn Young-joon)
A giant North Korean flag flutters on the top of a tower in the propaganda village of Gijeongdong, North Korea, as it is seen from South Korea's Taesungdong freedom village near the border village of Panmunjom on Friday, Feb. 15, 2013. (AP Photo/Jung Yeon-je, Pool)
South Korean Army's multiple rocket launcher fires live rounds during an exercise at Fire Training Field in Cheorwon, South Korea, Friday, Feb. 15, 2013. North Korea is upgrading one of its two major missile launch sites, apparently to handle much bigger rockets, and some design features suggest it is getting help from Iran, a U.S. research institute said Thursday. (AP Photo/Yonhap, Lee Sang-hack) KOREA OUT
In this Feb. 16, 2013 image made from video, North Korean leader Kim Jong Un, center, waves as he attends a statue unveiling ceremony at Mangyongdae Revolutionary School in Pyongyang, North Korea on the anniversary of late North Korean leader Kim Jong Il's birthday. (AP Photo/KRT via AP Video) TV OUT, NORTH KOREA OUT
North Korean army officers and soldiers attend a rally at Kim Il Sung Square on Thursday, Feb. 14, 2013, in Pyongyang, North Korea, in celebration of the country's recent nuclear test. The U.N. Security Council condemned North Korea's decision to conduct a third underground nuclear test earlier in the week in defiance of resolutions banning nuclear and missile activity. The writing reads "We warmly congratulate the 3rd successful underground nuclear test." (AP Photo/Jon Chol Jin)
PYONGYANG, North Korea (AP) ? North Korea warned the top American commander in South Korea on Saturday of "miserable destruction" if the U.S. military presses ahead with routine joint drills with South Korea set to begin next month.
Pak Rim Su, chief of North Korea's military delegation to the truce village of Panmunjom inside the Demilitarized Zone, sent the warning Saturday morning to Gen. James Thurman, Pyongyang's official Korean Central News Agency said, in a rare direct message to the U.S. commander.
The threat comes as the U.S. and other nations discuss how to punish North Korea for conducting an underground nuclear test on Feb. 12 in defiance of U.N. Security Council resolutions banning Pyongyang from nuclear and missile activity.
North Korea has characterized the nuclear test, its third since 2006, as a defensive act against U.S. aggression. Pyongyang accuses Washington of "hostility" for leading the charge to punish North Korea for a December rocket launch that the U.S. considers a covert missile test.
The U.S. and North Korea fought on opposite sides of the three-year Korean War, which ended in a truce in 1953, not a peace treaty, and left the Korean Peninsula divided by a heavily fortified border monitored by the U.S.-led U.N. Command.
Washington also stations 28,500 American troops in South Korea to protect its ally against North Korean aggression.
South Korea and the U.S. regularly conduct joint drills such as the Key Resolve and Foal Eagle exercises slated to take place next month. North Korea calls the drills proof of U.S. hostility, and accuses Washington of practicing for an invasion.
"You had better bear in mind that those igniting a war are destined to meet a miserable destruction," KCNA quoted Pak as saying in his message to Thurman. He called the drills "reckless."
North Korean leader Kim Jong Un, meanwhile, has been making a round of visits to military units guiding troops in drills and exercises since the nuclear test, KCNA said.
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Saturday, February 23, 2013
Rivera adjusting to new job as third-base coach
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